Let's get to know each other better: composition and forms of release of AugmentinAugmentin contains two substances: amoxicillin; clavulanic acid. Amoxicillin is a semisynthetic broad-spectrum penicillin antibiotic. It is practically an analogue of Ampicillin and differs only in small structural changes in the chemical formula. click here for the composition of Augmentin amoxicillin is in the form of trihydrate. Clavulanic acid is a fermentation product of gram-positive bacteria Streptomyces clavuligerus. This substance is part of Augmentin in the form of potassium salt.. Augmentin is distinguished by a wealth of release forms. GlaxoSmithKline produces many different dosages of the drug. When indicating the dosage, the manufacturer separately indicates the dose of the antibiotic (first digit) and clavulanate (second digit). Forms of release of the drug registered in Russia: Augmentin in the form of a dry powder for the preparation of an oral suspension that contains 200 mg + 28.5 mg in 5 ml of the finished medicine; Augmentin powder containing 400 mg + 57 mg in 5 ml of the finished suspension; The option in the form of a dry powder for the preparation of an oral suspension, which contains 125 mg + 31.25 mg in 5 ml of the finished medicine; Augmentin ES powder for the preparation of a children's suspension, which contains 600 mg + 42.9 mg in 5 ml; Augmentin powder, intended for the preparation of a solution for intravenous administration; 500mg tablets + 125mg; Tablets 875 mg + 125 mg; Augmentin tablets 250mg + 125 mg. Each tablet is coated with a film coating that protects the active substances from the action of the aggressive hydrochloric acid environment of the stomach.. Sometimes doctors, prescribing Augmentin, indicate the total dosage of the antibiotic and clavulanic acid. For example, you can often find a recipe of similar content: Tab.Augmentini 1000mg. Obviously, the doctor is referring to an antibiotic release form containing 875 mg of amoxicillin and 125 mg of clavulanic acid. Both the first and second dosage indication methods are equally true.. >> We recommend: if you are interested in effective methods of getting rid of chronic runny nose, pharyngitis, tonsillitis, bronchitis and persistent colds, be sure to look at this page of the site after reading this article. The information is based on the personal experience of the author and has helped many people, hopefully, will help you as well. Now back to the article. Augmentin 400 suspension dosage for childrenThe dosage regimen depends on several dominant factors, among them the age and current condition of the patient play an important role.. For adults and adolescents from 12 years of age, use in several variations is indicated. This is usually about pills.. For children from 3 months of age to 5 years, a special suspension is used. The dosage is calculated by body weight and is indicated in the instructions as the number of milligrams per kilogram of body weight in the daily period. If we are talking about such a dosage form as a suspension for children 125 / 31.25, then it is assumed 5 ml three times a day, that is, with an interval value of 8 hours. If this remedy is 200 milligrams per 28.5 in 5 ml, or 400 mg / 57 mg, then it is used twice a day with a break of 12 hours. For children from 6 years of age, the drug is prescribed traditionally as part of an identical dosage regimen. An important role is played by the price of the drug, which is from 300 rubles. So, we examined how Augmentin 400 suspension is used, a dosage for children to feel good. Only through a competent approach can an optimal result be achieved in terms of therapy. Healing propertiesThe active substance of Augmentin is represented by amoxicillin, which is a semi-synthetic antibiotic with a wide range of effects. High activity of the drug can be observed in relation to a number of harmonic (streptococci, Staphylococcus aureus, pneumococci) and gram-negative pathogenic flora (pertussis, cholera vibrio, gardnerella). Amoxicillin does not have a detrimental effect on microorganisms producing beta-lactamase, since under their influence there is a destruction of the antibiotic. The second active ingredient, namely clavulanic acid, is represented by a compound of beta-lactams, which can have a stopping effect on beta-lactamase and other enzymes that are resistant to penicillin group antibiotics and cephalosporins. Thus, clavulanic acid is a kind of protective shield of amoxicillin from the harmful effects of beta-lactamases, due to this the bacterial properties of Augmentin expand. Using oral Augmentin tablets, there is a rapid absorption of the active substances by the gastrointestinal mucosa. Optimum absorption rate can be achieved by taking tablets before meals.. With oral administration and intravenous injection, the main components of the drug penetrate into the tissues, as well as interstitial fluids. The relationship of the active substances of Augmentin with albumin is minimal. During active metabolization, the release of metabolites occurs by the kidneys, gastrointestinal tract, and also the respiratory system in the form of a carbon compound.